CELLULAR AND HUMORAL RESPONSE TO TRANSPLANTATION ANTIGENS

Cellular and Humoral Response to Transplantation Antigens

After transfer into heavily-irradiated allogeneic mice, spleen cells were found to produce two types of effector cells directed against the recipient alloantigens, namely alloantibody plaque-forming cells (PFC) and cytotoxic lymphocytes (CL). Both types of effector cells were detectable in vitro by virtue of their lytic effect on target cells carrying the recipient alloantigens. Alloantibody PF...

Cellular and Humoral Response to Transplantation Antigens I. Development of Alloantibody-forming Cells and Cytotoxic Lymprocytes

I t is generally accepted that the graft-versus-host (GVH) 1 reaction represents an immunological phenomenon called forth by the introduction of immunocompetent cells into a host carrying different transplantation antigens and incapable of rejecting the grafted cells (1, 2). Despite numerous studies, the actual mechanisms of the GYH reaction are poorly understood and, although there is ample ev...

Dissociation between humoral and cellular immune responses to lens antigens.

Rabbits immunized against lens extracts from various other (xenogeneic) species reacted well with the immunizing lens extracts by immunological assays measuring either humoral or cellular immune responses. A dissociation was observed, however, between the humoral and cellular immune responses when lenses from rabbit (allogeneic) or from nonimmunizing species were tested. Antibodies from these r...

Humoral Immune Response of Cultured Persian Sturgeon (Acipenser persicus) to Four Different Aeromonas hydrophila Antigens

[Evaluation of the humoral immune response to Strongyloides venezuelensis antigens].

Strongyloidiasis affects 30 million people in 70 countries. This enteral parasitosis is usually diagnosed using parasitological tests based on hydrotropism or thermotropism of larvae eliminated in feces, but these tests have been shown to have low sensitivity. In this study, antigenic extracts were tested by means of ELISA, immunoblotting and IFI, using filariform larvae of Strongyloides venezu...